Rudhra Joshi .

Hey, I'm Rudhra Joshi.

MS in Bioinformatics & Bachelor's in Pharmacy

Bioinformatics researcher specializing in drug discovery, single-cell sequencing, and computational biology. Skilled in bioinformatics software development, research automation, and cloud computing. Proficient in Python, R, and high-throughput data analysis for advancing medical research.

Bioinformatics | Medicinal Chemistry | Molecular Docking | Machine Learning | Deep Learning | Pharmacoinformatics | Drug Discovery | Computational Biology | Cancer Research | Molecular Dynamics | Structural Biology | Genetic Analysis | Evolutionary Genomics | Protein-Ligand Interactions | Single-cell RNA Sequencing | Statistical Mechanics | Cloud Computing | Google Cloud | AWS | Next.js | Node.js | Go | Docker | SQL | MongoDB | Kubernetes | Git Version Control | High-Performance Computing
Bioinformatics | Medicinal Chemistry | Molecular Docking | Machine Learning | Deep Learning | Pharmacoinformatics | Drug Discovery | Computational Biology | Cancer Research | Molecular Dynamics | Structural Biology | Genetic Analysis | Evolutionary Genomics | Protein-Ligand Interactions | Single-cell RNA Sequencing | Statistical Mechanics | Cloud Computing | Google Cloud | AWS | Next.js | Node.js | Go | Docker | SQL | MongoDB | Kubernetes | Git Version Control | High-Performance Computing

Research Experience.

Sorcery Dock

sorcery.rudrajoshi.me
2023 - 2024
Molecular Docking
Git Version Control
Molecular Visualizer
Text Editor
Software Development

Developed a bioinformatics platform to streamline molecular docking with Git-like version control and live molecular editing. Automated predictions using AWS and Google Cloud, enhancing scalability and accuracy using Autodock. Built with Next.js, Node.js, Go, and Docker, integrating SQL and MongoDB for efficient data management.

Triple-Negative Breast Cancer Drug Design (Grant)

blogs.rudrajoshi.me
2022 - 2023
Medicinal Chemistry
Computer Aided Drug Discovery

Awarded a 120,000 INR SSIP Hub grant to lead a team in designing, synthesizing, and evaluating anticancer drug candidates. Utilized molecular dynamics tools like Autodock and RDKit to predict receptor affinity of novel therapeutics.

Distributed System Design

Google Cloud Provider
Practice Project
Pub/Sub
Node.js
Sockets
Storage

Designed a distributed system using Google Cloud's Pub/Sub, App Run, and Next.js, alongside Node.js and Python Flask, featuring multiple endpoints for complex pharmaceutical workflows.

Skills and Hobbies

#1 Programming Languages

  • Python
  • Javascript
  • Typescript
  • Node.js
  • Julia
  • React.js
  • C++
  • C
  • Tailwind CSS
  • Slate.js
  • Framer Motion

#2Frameworks & Open Source

  • Next.js
  • Blender
  • Remix.js
  • Redhat
  • CCNA
  • AWS
  • Docker
  • Google Cloud Service
  • Github
  • System Design
  • Firebase Firestore
  • Google Cloud Storage
  • Flutter
  • Pub/Sub
  • Microsoft Excel
  • Microsoft Word
  • Pandas

#3Drug Discovery Tools

  • Rdkit
  • Open Babel API
  • Pymol
  • Dataset filteration
  • Discovery Studio
  • Autodock vina
  • Chemdraw 3d
  • Sorcery Dock

#4Books

  • The 4 Hours Work Week
  • Elon Musk - Ashlee Vance
  • The Warren Buffett Way
  • Outliers
  • Influence
  • Zero to One
  • Think and Grow Rich
  • The One Thing
  • Start With Why
  • Ikigai
  • Rich Dad Poor Dad
  • 7 Secrets of Persuasion
  • The Art of Thinking Clearly
  • Eat That Frog
  • How to Win Friends and Influence People
  • The Psychology of Money
  • The Compound Effect
  • The New One Minute Manager
  • The Leader In You
  • The Power of Your Subconscious Mind
  • Never Split the Difference
  • How to Talk to Anyone
  • Deep Work
  • Instant Self-Hypnosis

Latest Blog Posts

Understanding Molecular Evolution

Exploring evolutionary changes at the molecular level with an emphasis on genetic and protein modifications, including practical bioinformatics applications in phylogenetics and molecular clock theory.

Bioinformatics
Evolution
Genetics
8/12/2024
10 min

Drug Discovery Basics

An introduction to computational drug discovery techniques, covering key methods like molecular docking, QSAR, and ligand-based virtual screening. Ideal for bioinformaticians entering pharmacoinformatics.

Drug Discovery
Computational Biology
Pharmacoinformatics
6/24/2024
8 min

Single-Cell Sequencing in Cancer Research

A deep dive into the role of scRNA-seq in cancer studies, focusing on its applications for tumor heterogeneity and precision medicine.

Cancer Research
Single-Cell Analysis
Genomics
5/15/2024
12 min

Data Acquisition in Bioinformatics

Overview of efficient methods for acquiring datasets in bioinformatics, including resources like NCBI, GenBank, and EMBL, with a focus on open-source data for large-scale analyses.

Data Science
Bioinformatics
Data Acquisition
3/20/2024
7 min

EADock: Evolutionary Algorithms for Molecular Docking

Explains the EADock algorithm and its role in docking small molecules into protein active sites using multiobjective evolutionary optimization, highlighting its utility in structure-based drug design.

Molecular Docking
Drug Design
Evolutionary Algorithms
1/28/2024
15 min

TeachOpenCADD: Computer-Aided Drug Design with Python

A guide to using the TeachOpenCADD library for computational drug design in Python, covering core techniques like molecular modeling, docking, and cheminformatics applications.

Drug Design
Python
Open Source
11/2/2023
11 min